Description

Methocarbamol-D5 CAS NO 1189699-70-4 is a deuterated internal standard specifically designed for analytical applications, featuring five deuterium atoms replacing hydrogen at key positions. This compound is essential for ensuring the accuracy and reliability of quantitative analysis, particularly in mass spectrometry-based methods. It is a critical tool for pharmaceutical researchers, analytical chemists, and quality control laboratories involved in drug metabolism and pharmacokinetic (DMPK) studies, bioanalytical method development, and forensic toxicology.

Application

• Quantitative Internal Standard for the accurate measurement of Methocarbamol in biological matrices (e.g., plasma, serum, urine) using LC-MS/MS and GC-MS.
• Drug Metabolism and Pharmacokinetics (DMPK) studies to track the absorption, distribution, metabolism, and excretion of Methocarbamol.
• Bioanalytical Method Development and Validation, where it is used to correct for matrix effects and instrument variability.
• Forensic and Clinical Toxicology testing for the precise quantification of Methocarbamol in cases of overdose or therapeutic drug monitoring.
• Pharmaceutical Quality Control and stability testing of Methocarbamol-containing formulations.
• Isotope Dilution Mass Spectrometry (IDMS), a definitive method for achieving high-precision analytical results.

Basic Information

Product Name	Methocarbamol-D5
CAS No.	1189699-70-4
Molecular Formula	C11H10D5NO5
Molecular Weight	247.29 g/mol
Synonyms	Methocarbamol-d5; 3-(2-Methoxyphenoxy)-1,2-propanediol 1-carbamate-d5; Guaifenesin carbamate-d5; Robaxin-d5; AHR-85-d5; [2H5]-Methocarbamol; Deuterated Methocarbamol; Methocarbamol (phenyl-d5)
EINECS	Contact for details

Quality Control

Our Methocarbamol-D5 is manufactured under strict quality systems to ensure the high chemical purity and isotopic enrichment required for sensitive analytical applications. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR, HPLC, and mass spectrometry, to confirm identity, chemical purity, and deuterium incorporation. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Chemical Purity (by HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.