Description

4-Methoxy-2,3,6-Trimethylbenzyl Bromide-D3 is a deuterium-labeled isotopologue of a key benzyl bromide intermediate, essential for creating stable isotope-labeled compounds. This high-purity labeled building block is critical for applications requiring precise analytical tracking and metabolic studies, ensuring data integrity and reliability. It is primarily utilized by research institutions and pharmaceutical companies engaged in advanced organic synthesis, analytical method development, and the production of deuterated active pharmaceutical ingredients (APIs).

Application

• As a deuterated synthetic intermediate in the preparation of isotopically labeled pharmaceutical compounds for drug metabolism and pharmacokinetics (DMPK) studies.
• Use in internal standard synthesis for accurate quantification in mass spectrometry-based analytical methods (LC-MS, GC-MS).
• Key building block for advanced organic synthesis in medicinal chemistry research, particularly for structure-activity relationship (SAR) exploration.
• Production of deuterium-labeled fine chemicals and specialty materials for academic and industrial research.
• Development of tracer compounds used in mechanistic studies within chemical and biochemical research.

Basic Information

Product Name	4-Methoxy-2,3,6-Trimethylbenzyl Bromide-D3
CAS No.	1189693-80-8
Molecular Formula	C11H12D3BrO
Molecular Weight	246.17 g/mol (approx.)
Synonyms	2,3,6-Trimethyl-4-methoxybenzyl-d3 Bromide; (2,3,6-Trimethyl-4-methoxyphenyl-d3)methyl Bromide; 4-Methoxy-2,3,6-trimethylbenzyl-α,α,α-d3 Bromide; 1-(Bromomethyl)-2,3,6-trimethyl-4-methoxybenzene-d3; Deuterated 4-Methoxy-2,3,6-Trimethylbenzyl Bromide; Trimethylmethoxybenzyl Bromide-D3; TMTMB-D3; Isotopically Labeled Benzyl Bromide Intermediate
EINECS	Contact for details

Quality Control

Our 4-Methoxy-2,3,6-Trimethylbenzyl Bromide-D3 is manufactured under strict quality systems to ensure high chemical and isotopic purity suitable for sensitive research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, isotopic enrichment (D-content), and impurity profile. We adhere to rigorous analytical standards, utilizing techniques including NMR, HPLC, and mass spectrometry for verification.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.