Description

n-tert-Boc-2-(4-Hydroxy-2-Methoxyphenoxy)Ethylamine-D3 is a deuterated, Boc-protected aminoethylphenol derivative, a high-value building block designed for advanced chemical synthesis. This compound is critical for researchers and manufacturers requiring precise isotopic labeling to study metabolic pathways, enhance pharmacokinetic properties, or develop stable isotope-labeled standards for analytical methods. It is primarily utilized in pharmaceutical R&D, agrochemical discovery, and analytical chemistry for applications where tracking molecular fate or improving detection sensitivity is paramount.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of deuterated drug candidates, potentially improving metabolic stability and bioavailability.
• Metabolic Pathway Tracer: Used as a stable isotope-labeled precursor in pharmacokinetic and ADME (Absorption, Distribution, Metabolism, Excretion) studies.
• Analytical Reference Standard: Employed as an internal standard in LC-MS and GC-MS for the accurate quantification of related compounds in complex matrices.
• Agrochemical Research: Acts as a building block for developing novel, labeled agrochemicals and studying their environmental fate.
• Chemical Biology Probe: Useful for creating tagged molecules to investigate biological mechanisms and protein interactions.
• Material Science Research: Potential precursor for specialized polymers or coatings where isotopic purity is a factor.

Basic Information

Product Name	n-tert-Boc-2-(4-Hydroxy-2-Methoxyphenoxy)Ethylamine-D3
CAS No.	1189659-07-1
Molecular Formula	C₁₄H₁₈D₃NO₅
Molecular Weight	286.35 g/mol
Synonyms	2-[(tert-Butoxycarbonyl)amino]ethyl 4-hydroxy-2-methoxyphenyl ether-d3; 2-(Boc-amino)ethyl 4-hydroxy-2-methoxyphenyl ether-d3; tert-Butyl N-[2-[(4-hydroxy-2-methoxyphenoxy)ethyl-d3]]carbamate; Boc-2-(4-Hydroxy-2-methoxyphenoxy)ethylamine-d3; Deuterated Boc-protected aminoethyl guaiacol; 2-[(tert-Butoxycarbonyl-D9)amino]ethyl 4-hydroxy-2-methoxyphenyl ether (common mislabeling); 2-(4-Hydroxy-2-methoxyphenoxy)ethylamine-D3 N-Boc derivative
EINECS	Contact for details

Quality Control

Our n-tert-Boc-2-(4-Hydroxy-2-Methoxyphenoxy)Ethylamine-D3 is manufactured under strict quality control protocols to ensure high isotopic and chemical purity, essential for research integrity. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment (D3), chemical purity by HPLC, and identity confirmation. We adhere to cGMP principles where applicable, ensuring traceability and consistency for critical pharmaceutical and analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere (e.g., nitrogen or argon) after each use to prevent degradation. For long-term storage, consider refrigeration at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D3, MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.