Description

4-[1,1,2,2-Tetradeuterio-2-[5-(2-Methyl-1,3-Dioxolan-2-Yl)Pyridin-2-Yl]Ethoxy]Benzaldehyde is a deuterated aldehyde derivative, serving as a crucial advanced pharmaceutical intermediate for the development of novel therapeutic agents. Its primary value lies in its role as a labeled building block for pharmacokinetic and metabolic studies, enabling precise drug tracking and mechanism-of-action research. This compound is essential for R&D and manufacturing teams in the pharmaceutical, biotechnology, and contract research organization (CRO) sectors.

Application

• Deuterated Drug Synthesis: Key intermediate for incorporating deuterium atoms into new chemical entities (NCEs) to create deuterium-labeled pharmaceuticals.
• Metabolic Pathway Tracing: Used in the synthesis of internal standards and probes for mass spectrometry-based drug metabolism and pharmacokinetics (DMPK) studies.
• Medicinal Chemistry Research: A versatile building block for structure-activity relationship (SAR) optimization and the development of targeted therapies.
• Isotope-Labeled Compound Production: Serves as a precursor for manufacturing stable isotope-labeled compounds used in analytical standards and bioanalytical assays.
• Academic and Industrial R&D: Facilitates fundamental research in organic synthesis and the exploration of deuterium isotope effects in biological systems.

Basic Information

Item	Details
Product Name	4-[1,1,2,2-Tetradeuterio-2-[5-(2-Methyl-1,3-Dioxolan-2-Yl)Pyridin-2-Yl]Ethoxy]Benzaldehyde
CAS No.	1189653-26-6
Molecular Formula	C18H18D4NO4
Molecular Weight	322.40 g/mol
Synonyms	4-[2-Deuterio-2-(5-(2-methyl-1,3-dioxolan-2-yl)pyridin-2-yl)ethoxy]benzaldehyde-d3; Benzaldehyde, 4-[1,1,2,2-tetradeuterio-2-[5-(2-methyl-1,3-dioxolan-2-yl)-2-pyridinyl]ethoxy]-; Deuterated 4-[2-[5-(2-Methyl-1,3-dioxolan-2-yl)pyridin-2-yl]ethoxy]benzaldehyde; 4-(2-(5-(2-Methyl-1,3-dioxolan-2-yl)pyridin-2-yl)ethoxy)benzaldehyde-d4; CAS 1189653-26-6
EINECS	Contact for details

Quality Control

Our high-purity deuterated intermediates are manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ¹³C, and deuterium), HPLC, and mass spectrometry, to confirm chemical identity, isotopic enrichment, and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research and development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Deuterium Enrichment (MS/NMR)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.