Description

8-Chloro-6-(2,2,3,3,5,5,6,6-Octadeuteriopiperazin-1-Yl)Benzo[B][1,4]Benzoxazepin-3-Ol is a deuterated derivative of a benzoxazepine-based compound, designed for advanced research and development applications. This compound is of significant interest for its utility as a stable isotope-labeled internal standard or a metabolic tracer in pharmacokinetic and drug metabolism studies. It is primarily targeted at pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in analytical method development and bioanalytical research for novel therapeutic agents.

Application

• As a stable isotope-labeled internal standard for the precise quantification of its non-deuterated counterpart in biological matrices using LC-MS/MS.
• In drug metabolism and pharmacokinetics (DMPK) studies to investigate absorption, distribution, metabolism, and excretion (ADME) profiles.
• For use in analytical method development and validation to ensure accuracy, precision, and regulatory compliance in bioanalysis.
• As a critical reagent in metabolite identification and structural elucidation research.
• In preclinical and clinical research for novel benzoxazepine-based pharmaceutical candidates.
• Supporting proteomics and biomarker discovery research where precise chemical tools are required.

Basic Information

Item	Details
Product Name	8-Chloro-6-(2,2,3,3,5,5,6,6-Octadeuteriopiperazin-1-Yl)Benzo[B][1,4]Benzoxazepin-3-Ol
CAS No.	1189505-24-5
Molecular Formula	C19H11D8ClN4O2
Molecular Weight	Contact for details
Synonyms	8-Chloro-6-(octadeuteriopiperazin-1-yl)benzo[b][1,4]benzoxazepin-3-ol; Deuterated Benzoxazepine Derivative; 8-Chloro-6-(piperazine-d8-1-yl)benzo[b][1,4]benzoxazepin-3-ol; 1189505-24-5; Benzoxazepine-d8; Stable Isotope Labeled Benzoxazepine; (8-Chloro-3-hydroxybenzo[b][1,4]benzoxazepin-6-yl)-octadeuteriopiperazine; Deuterated Internal Standard for Benzoxazepine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research chemicals. Each batch is characterized to confirm identity, isotopic purity, and chemical purity. Certificates of Analysis (COA) are available upon request, providing detailed results from analytical techniques such as NMR, HPLC, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This compound is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Purity (MS)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.