Description

4-Methoxy-2,3,6-Trimethylbenzyl Alcohol-D3 is a deuterium-labeled derivative of a substituted benzyl alcohol, a crucial tool compound for advanced research and development. This stable isotope-labeled analog is essential for creating internal standards in quantitative mass spectrometry, ensuring unparalleled accuracy in analytical measurements. It is primarily needed by pharmaceutical researchers, agrochemical developers, and analytical laboratories engaged in pharmacokinetic studies, metabolic profiling, and high-precision trace analysis.

Application

• Internal Standard for LC-MS/MS: Serves as a critical, non-interfering reference standard for the precise quantification of its non-deuterated counterpart in complex biological matrices like plasma, urine, and tissue homogenates.
• Metabolism and Pharmacokinetic (PK/PD) Studies: Enables accurate tracking of drug absorption, distribution, metabolism, and excretion (ADME) by mitigating matrix effects and ion suppression in mass spectrometric detection.
• Deuterium-Labeled Intermediate: Used in the synthesis of more complex deuterated molecules for use in mechanistic studies, stable isotope probing, and as tracers in chemical and biological systems.
• Analytical Method Development and Validation: Provides a reliable standard for developing, optimizing, and validating highly sensitive and specific analytical methods in compliance with GLP and GMP guidelines.
• Impurity Profiling and Reference Standard: Acts as a certified reference material for identifying and quantifying process-related impurities or degradation products in active pharmaceutical ingredient (API) batches.

Basic Information

Product Name	4-Methoxy-2,3,6-Trimethylbenzyl Alcohol-D3
CAS No.	1189501-77-6
Molecular Formula	C12H15D3O2
Molecular Weight	197.28 g/mol
Synonyms	(2,3,6-Trimethyl-4-methoxyphenyl)methan-d3-ol; 4-Methoxy-2,3,6-trimethylbenzenemethanol-d3; Deuterated 4-Methoxy-2,3,6-Trimethylbenzyl Alcohol; [D3]-4-Methoxy-2,3,6-Trimethylbenzyl Alcohol; 2,3,6-Trimethyl-4-methoxybenzyl-d3 Alcohol; (4-Methoxy-2,3,6-trimethylphenyl)methanol-d3; Benzenemethanol-d3, 4-methoxy-2,3,6-trimethyl-
EINECS	Contact for details

Quality Control

Every batch of 4-Methoxy-2,3,6-Trimethylbenzyl Alcohol-D3 is produced and analyzed under strict quality systems. We guarantee high chemical and isotopic purity, with comprehensive testing including assay, deuterium enrichment (D-content), and identification. A detailed Certificate of Analysis (COA) providing batch-specific data from techniques like NMR, HPLC, and MS is supplied with each shipment to ensure traceability and support your regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuterium Enrichment (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.