Description

Bromopride-D3 is a deuterium-labeled internal standard of the antiemetic and prokinetic agent Bromopride, specifically designed for high-precision analytical applications. This stable isotope-labeled compound is essential for ensuring the accuracy and reliability of quantitative mass spectrometry analyses, particularly in pharmacokinetic and metabolism studies. It is a critical reagent for pharmaceutical R&D laboratories, contract research organizations (CROs), and regulatory testing facilities focused on drug development and bioanalytical method validation.

Application

• Primary use as an internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS/MS) for the quantification of Bromopride in biological matrices.
• Critical for pharmacokinetic studies and drug metabolism research to track absorption, distribution, metabolism, and excretion (ADME) profiles.
• Enhances method validation in bioanalytical assays for regulatory submissions to agencies like the FDA and EMA.
• Used in doping control and forensic toxicology to accurately detect and quantify Bromopride.
• Supports clinical research and therapeutic drug monitoring (TDM) programs.
• Essential for pharmaceutical quality control labs performing impurity profiling and stability testing.

Basic Information

Product Name	Bromopride-D3
CAS No.	1189498-49-4
Molecular Formula	C14H19D3BrN3O2
Molecular Weight	341.24 g/mol (approx.)
Synonyms	4-Amino-5-bromo-N-[(2-diethylamino)ethyl]-2-methoxybenzamide-D3; 4-Amino-5-bromo-N-[2-(diethylamino)ethyl]-o-anisamide-D3; Bromopride (methyl-d3); Bromopride-d3 (deuterated); Valopride-D3; CAS 1189498-49-4
EINECS	Contact for details

Quality Control

Our Bromopride-D3 is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for sensitive analytical applications. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR, HPLC, and mass spectrometry, to confirm identity, isotopic enrichment (typically ≥98 atom % D), and chemical purity (typically ≥95%). A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Isotopic Purity	≥ 98 atom % D
Chemical Purity	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.