Description

4-Methyl-2-Pyridin-2-Yl-2-[1,1,2,2-Tetradeuterio-2-[Di(Propan-2-Yl)Amino]Ethyl]Pentanamide is a deuterated organic compound of significant interest in advanced pharmaceutical research and development. Its core value lies in its utility as a stable isotope-labeled internal standard or a key synthetic intermediate for pharmacokinetic and metabolic studies. This high-purity specialty chemical is primarily needed by pharmaceutical companies, contract research organizations (CROs), and academic institutions engaged in drug discovery and analytical method development. The compound, identified by CAS NO 1189498-03-0, enables precise quantification and reliable data in complex biological matrices.

Application

• Pharmaceutical Research: Serves as a deuterium-labeled internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the accurate bioanalysis of drug candidates.
• Metabolite Identification: Used in drug metabolism and pharmacokinetics (DMPK) studies to track and identify metabolites, aiding in understanding a compound's metabolic fate.
• Proteomics & Biomarker Discovery: Can be utilized in chemical proteomics or as a building block for isotopic labeling in quantitative proteomic workflows.
• Synthetic Intermediate: Acts as a key deuterated precursor in the multi-step synthesis of more complex labeled target molecules for clinical trials.
• Quality Control & Method Validation: Employed in analytical laboratories to develop and validate robust, sensitive, and specific assay methods for new chemical entities.

Basic Information

Product Name	4-Methyl-2-Pyridin-2-Yl-2-[1,1,2,2-Tetradeuterio-2-[Di(Propan-2-Yl)Amino]Ethyl]Pentanamide
CAS No.	1189498-03-0
Molecular Formula	C19H29D4N3O
Molecular Weight	319.50 g/mol (for deuterated form)
Synonyms	4-Methyl-2-(pyridin-2-yl)-2-[2-[bis(propan-2-yl)amino]-1,1,2,2-tetradeuterioethyl]pentanamide; 2-(2-(Diisopropylamino)-1,1,2,2-d4-ethyl)-4-methyl-2-(pyridin-2-yl)pentanamide; Deuterated Diisopropylaminoethyl Pentanamide Derivative; d4-Labeled Pyridine Amide; (2R/S)-4-Methyl-2-(pyridin-2-yl)-2-[2-(diisopropylamino)-1,1,2,2-d4-ethyl]pentanamide; 1189498-03-0; Pentanamide, 4-methyl-2-(2-pyridinyl)-2-[2-[bis(1-methylethyl)amino]-1,1,2,2-d4-ethyl]-
EINECS	Contact for details

Quality Control

Our 4-Methyl-2-Pyridin-2-Yl-2-[1,1,2,2-Tetradeuterio-2-[Di(Propan-2-Yl)Amino]Ethyl]Pentanamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, and ²H) for isotopic enrichment verification and HPLC for chemical and isomeric purity. We provide comprehensive Certificates of Analysis (COA) detailing all specifications, ensuring compliance with the stringent requirements of pharmaceutical R&D. Custom synthesis and specific purity grades (e.g., >98%, >99%) are available to meet your project's exact needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure (¹H, ¹³C, ²H)
Purity (HPLC)	≥ 98.0%
Isomeric Purity	≥ 95.0% (by chiral HPLC, if applicable)
Deuterium Enrichment (²H NMR)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.