Description

4-[2-(5-Ethyl-2-Pyridinyl)-D4-Ethoxy]-Benzaldehyde is a high-purity, deuterated aromatic aldehyde compound, serving as a critical advanced intermediate in pharmaceutical research and development. Its core value lies in enabling precise metabolic and pharmacokinetic studies through the strategic incorporation of stable deuterium isotopes. This compound is essential for researchers and manufacturers in the pharmaceutical industry, particularly those developing novel active pharmaceutical ingredients (APIs) and conducting sophisticated drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of deuterated drug candidates for improved metabolic stability and pharmacokinetic profiles.
• Metabolic Studies: Used as a labeled precursor in the development of internal standards for Liquid Chromatography-Mass Spectrometry (LC-MS) bioanalytical assays.
• Drug Discovery Research: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of novel chemical entities.
• Isotope Labeling: Serves as a source of deuterium for the preparation of isotopically labeled compounds used in mechanistic and tracer studies.
• Chemical Reference Standard: Utilized as a high-purity certified reference material (CRM) for analytical method development and validation.

Basic Information

Product Name	4-[2-(5-Ethyl-2-Pyridinyl)-D4-Ethoxy]-Benzaldehyde
CAS No.	1189479-80-8
Molecular Formula	C₁₆H₁₃D₄NO₂
Molecular Weight	259.33 g/mol
Synonyms	4-[2-(5-Ethyl-2-pyridinyl)-1,1,2,2-tetradeuteroethoxy]benzaldehyde; Benzaldehyde, 4-[2-(5-ethyl-2-pyridinyl)-1,1,2,2-tetradeuteroethoxy]-; 4-[(5-Ethylpyridin-2-yl)-D4-ethoxyl]benzaldehyde; Deuterated 4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzaldehyde; 4-(2-(5-Ethyl-2-pyridyl)-D4-ethoxy)benzaldehyde
EINECS	Contact for details

Quality Control

Our 4-[2-(5-Ethyl-2-Pyridinyl)-D4-Ethoxy]-Benzaldehyde is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity suitable for research and development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and impurity profiles, typically determined by advanced analytical techniques including NMR, HPLC, and LC-MS. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuterium Enrichment (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.