Description

Diethyl-(6-Chloro-2-Carbazolyl)Methyl-D3 Malonate is a high-purity, deuterated chemical intermediate of significant importance in advanced pharmaceutical research and development. This compound is specifically valued for its role in the synthesis of deuterated drug candidates, where the incorporation of deuterium can enhance metabolic stability and improve pharmacokinetic profiles. It is primarily needed by research scientists and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries working on novel active ingredients and isotopic labeling studies.

Application

• Deuterated Pharmaceutical Intermediate: A key building block in the synthesis of deuterium-labeled drug molecules for metabolic and pharmacokinetic studies.
• Isotope Labeling Reagent: Used in the preparation of isotopically labeled standards for analytical methods like LC-MS, enhancing detection accuracy and reliability.
• Organic Synthesis Research: Serves as a versatile intermediate in complex organic synthesis, particularly for constructing carbazole-based molecular frameworks.
• Agrochemical Development: Employed in the research and development of novel, deuterated agrochemicals to explore improved efficacy and environmental profiles.
• Material Science Precursor: Investigated as a precursor for the development of advanced organic electronic materials due to the carbazole core structure.

Basic Information

Product Name	Diethyl-(6-Chloro-2-Carbazolyl)Methyl-D3 Malonate
CAS No.	1189473-03-7
Molecular Formula	C22H20D3ClNO4
Molecular Weight	404.90 g/mol (deuterated form)
Synonyms	Diethyl (6-Chloro-2-carbazolyl)(methyl-d3)malonate; Diethyl [(6-Chloro-2-carbazolyl)(methyl-d3)]propanedioate; (6-Chloro-9H-carbazol-2-yl)(methyl-d3)malonic Acid Diethyl Ester; Diethyl (6-Chloro-9H-carbazol-2-yl)(methyl-d3)malonate; Malonic acid, (6-chloro-9H-carbazol-2-yl)(methyl-d3)-, diethyl ester; Deuterated Diethyl (6-Chloro-2-carbazolyl)methylmalonate; d3-Diethyl (6-Chloro-2-carbazolyl)methylmalonate
EINECS	Contact for details

Quality Control

Our Diethyl-(6-Chloro-2-Carbazolyl)Methyl-D3 Malonate is manufactured under strict quality control protocols to ensure high chemical purity and isotopic enrichment. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as chemical purity, deuterium incorporation (D-enrichment), and impurity profiles. We adhere to cGMP guidelines where applicable, ensuring traceability and consistency for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuterium Enrichment (NMR/MS)	≥ 98 atom % D
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.