Description

Saccharin-D4 CAS NO 1189466-17-8 is a high-purity, stable isotope-labeled analog of saccharin, where four hydrogen atoms are replaced by deuterium. This isotopic labeling is critical for providing an internal standard in quantitative analytical methods, ensuring unparalleled accuracy and reliability in measurement. It is an essential material for research and quality control laboratories in the pharmaceutical, food science, and analytical chemistry sectors that require precise quantification of saccharin.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a deuterated internal standard in LC-MS/MS and GC-MS analyses for the accurate quantification of saccharin in complex matrices.
• Pharmaceutical Research & Metabolism Studies: Enables precise tracking and pharmacokinetic analysis of saccharin and related compounds in drug development and metabolic pathway investigations.
• Food & Beverage Safety Testing: Facilitates reliable monitoring and compliance testing for saccharin content in food products, beverages, and dietary supplements.
• Environmental Analysis: Applied in the detection and quantification of artificial sweeteners in water and environmental samples.
• Method Development & Validation: Serves as a key reference material for developing, calibrating, and validating new analytical methods in regulatory and contract laboratories.
• Clinical Diagnostics: Supports accurate measurement in bioanalytical assays for human exposure or metabolic studies.

Basic Information

Product Name	Saccharin-D4
CAS No.	1189466-17-8
Molecular Formula	C7H3D4NO3S
Molecular Weight	187.21 g/mol
Synonyms	1,2-Benzisothiazol-3(2H)-one-4,5,6,7-d4, 1,1-Dioxide; 2,3-Dihydro-3-oxobenzisosulfonazole-d4; Deuterated Saccharin; Saccharin-d4; Benzoic sulfimide-d4; 2-Sulfobenzoic acid imide-d4; o-Sulfobenzimide-d4; Gluside-d4
EINECS	Contact for details

Quality Control

Our Saccharin-D4 is manufactured under strict quality control protocols to ensure high isotopic purity and chemical integrity, suitable for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment (D-atom %), chemical purity (by HPLC), and identity confirmation (by NMR and MS). We support compliance with GMP and ISO guidelines for reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-atom %)	≥ 98.0%
Deuterium Content (MS)	≥ 98.0% (4 atoms D)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.