Description

3-(2-Chloroethyl-D4)-2-Methyl-4H-Pyrido[1,2-A]Pyrimidin-4-One is a deuterated organic compound of significant interest in advanced chemical research and development. This deuterium-labeled analog is primarily valued for its utility as a stable isotope-labeled internal standard in analytical chemistry, enabling precise quantification and metabolic studies. It is essential for researchers and developers in the pharmaceutical, agrochemical, and life science sectors who require high-purity, structurally-defined compounds for mass spectrometry, pharmacokinetics, and tracer studies.

Application

• Internal Standard for LC-MS/MS: Serves as a critical, non-interfering reference standard in quantitative bioanalytical methods for drug discovery and development.
• Metabolic Pathway Tracing: Used in deuterium labeling studies to investigate the metabolic fate and biotransformation pathways of pharmaceutical compounds.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of process-related impurities and degradants during API development.
• Isotope Dilution Mass Spectrometry (IDMS): Enables highly accurate and precise measurement of target analytes in complex matrices, enhancing data reliability.
• Chemical Reference Material: Provides a certified reference material for calibrating analytical instruments and validating testing methodologies in quality control laboratories.
• Precursor for Labeled Compounds: Acts as a specialized synthetic intermediate for the preparation of more complex deuterated molecules for research.

Basic Information

Product Name	3-(2-Chloroethyl-D4)-2-Methyl-4H-Pyrido[1,2-A]Pyrimidin-4-One
CAS No.	1189465-23-3
Molecular Formula	C11H9D4ClN2O
Molecular Weight	224.71 g/mol
Synonyms	2-Methyl-3-(2-chloroethyl-d4)-4H-pyrido[1,2-a]pyrimidin-4-one; 3-(2-Chloroethyl-1,1,2,2-d4)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one; Deuterated 3-(2-Chloroethyl)-2-methylpyridopyrimidinone; 1189465-23-3; d4-Labeled Chloroethyl Methylpyridopyrimidinone; 2-Methyl-3-(2-chloroethyl-d4)pyrido[1,2-a]pyrimidin-4-one; 3-(2-Chloroethyl-d4)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
EINECS	Contact for details

Quality Control

Every batch of 3-(2-Chloroethyl-D4)-2-Methyl-4H-Pyrido[1,2-A]Pyrimidin-4-One is manufactured and tested under strict quality management systems. We guarantee high chemical and isotopic purity, with comprehensive characterization using advanced techniques including NMR (¹H, ¹³C), HPLC, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, isotopic enrichment (D-content), and confirming identity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.