Description

2-Amino-3-Methyl-9H-Pyrido[2,3-B]Indole-D3 is a deuterated isotopologue of the heterocyclic aromatic amine, specifically labeled with three deuterium atoms. This compound is of significant value as a stable isotope-labeled internal standard for precise analytical quantification. It is primarily required by research and analytical laboratories in the pharmaceutical, food safety, and environmental monitoring sectors for advanced mass spectrometry applications such as LC-MS/MS.

Application

• Internal Standard for Mass Spectrometry: Serves as a critical stable isotope-labeled internal standard (SIL-IS) for the accurate quantification of its non-deuterated counterpart in complex matrices.
• Pharmaceutical Research: Used in pharmacokinetic and metabolic studies to track drug candidates and their metabolites with high specificity and minimal interference.
• Food Safety Analysis: Essential for the detection and quantification of heterocyclic aromatic amines (HAAs), which are potential food-borne mutagens and carcinogens formed during high-temperature cooking.
• Toxicology and Biomarker Research: Employed in studies investigating exposure biomarkers and the metabolic activation pathways of mutagenic compounds.
• Method Development and Validation: A key reagent for developing and validating sensitive, robust, and compliant analytical methods in regulated environments.
• Reference Material: Used as a high-purity certified reference material (CRM) to ensure the accuracy and traceability of analytical results.

Basic Information

Product Name	2-Amino-3-Methyl-9H-Pyrido[2,3-B]Indole-D3
CAS No.	1189458-14-7
Molecular Formula	C12H8D3N3
Molecular Weight	200.25 g/mol
Synonyms	2-Amino-3-methyl-9H-pyrido[2,3-b]indole-d3; MeAαC-d3; 2-Amino-3-methyl-9H-pyrido[2,3-b]indole (methyl-d3); 3-Methyl-2-amino-9H-pyrido[2,3-b]indole-d3; 2-Amino-3-methyl-α-carboline-d3; Deuterated MeAαC; [D3]-2-Amino-3-methyl-9H-pyrido[2,3-b]indole; Stable Isotope Labeled MeAαC
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Methyl-9H-Pyrido[2,3-B]Indole-D3 is manufactured under strict quality systems to ensure the highest isotopic and chemical purity required for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic purity (D-enrichment), chemical purity by HPLC, and identity confirmation. We adhere to relevant guidelines for the production of reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at 2-8°C. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.