Description

5-Methyl-n-[2-[4-[(1,2,2,3,3,4,4,5,5,6,6-Undecadeuteriocyclohexyl)Carbamoylsulfamoyl]Phenyl]Ethyl]Pyrazine-2-Carboxamide is a deuterated organic compound of significant interest in advanced research and development. This compound is valued for its role as a stable isotope-labeled internal standard, which is critical for ensuring analytical accuracy and reliability in quantitative studies. It is primarily sought by research institutions and pharmaceutical companies engaged in metabolomics, pharmacokinetic analysis, and drug discovery programs where precise measurement is paramount.

Application

• Internal Standard for LC-MS/MS: Used as a deuterium-labeled reference standard in liquid chromatography-tandem mass spectrometry for the accurate quantification of its non-deuterated counterpart or related metabolites.
• Pharmaceutical R&D: Essential in drug metabolism and pharmacokinetics (DMPK) studies to track drug absorption, distribution, metabolism, and excretion (ADME).
• Biomarker Analysis: Employed in clinical and preclinical research for the sensitive and specific detection of biomarkers in complex biological matrices.
• Metabolomics Research: Facilitates precise quantitative analysis in metabolic pathway studies and profiling.
• Method Development & Validation: Serves as a critical component in developing and validating robust analytical methods in compliance with regulatory guidelines (e.g., FDA, EMA).
• Chemical Reference Material: Provides a high-purity, characterized material for calibration and quality control in analytical laboratories.

Basic Information

Product Name	5-Methyl-n-[2-[4-[(1,2,2,3,3,4,4,5,5,6,6-Undecadeuteriocyclohexyl)Carbamoylsulfamoyl]Phenyl]Ethyl]Pyrazine-2-Carboxamide
CAS No.	1189426-07-0
Molecular Formula	C21H17D11N5O4S
Molecular Weight	~475.62 g/mol
Synonyms	5-Methyl-N-[2-[4-[(undecadeuteriocyclohexyl)carbamoyl]sulfamoyl]phenyl]ethyl]pyrazine-2-carboxamide; Deuterated Cyclohexyl Sulfonylurea Derivative; [D11]-Labeled Analog; 1189426-07-0; 5-Methyl-pyrazine-2-carboxylic acid [2-[4-[(1,2,2,3,3,4,4,5,5,6,6-undecadeuterio-cyclohexylcarbamoyl)-sulfamoyl]-phenyl]-ethyl]-amide
EINECS	Contact for details

Quality Control

Our deuterated compounds are manufactured under strict quality control protocols to ensure the highest isotopic purity and chemical integrity. Each batch is analyzed using advanced techniques including NMR, HPLC, and mass spectrometry to confirm identity, chemical purity, and deuterium enrichment. Certificates of Analysis (COA) detailing lot-specific data are provided and can be tailored to meet specific research or regulatory submission requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage at -20°C under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 99.0 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.