Description

2-Amino-3,7,8-Trimethyl-3H-Imidazo[4,5-F]Quinoxaline-D3 is a deuterium-labeled analog of a heterocyclic aromatic amine, specifically designed for use as an internal standard in advanced analytical chemistry. This compound is critical for ensuring the accuracy and reliability of quantitative analyses, particularly in mass spectrometry, by correcting for variations in sample preparation and instrument performance. It is an essential tool for researchers and quality control laboratories in the pharmaceutical, food safety, and environmental monitoring sectors who require precise measurement of trace-level compounds.

Application

• Internal Standard for Mass Spectrometry (MS): Primary application as a stable isotope-labeled internal standard for the accurate quantification of its non-deuterated counterpart and related compounds in LC-MS/MS and GC-MS analyses.
• Pharmaceutical Research & Metabolism Studies: Used in pharmacokinetic, pharmacodynamic, and drug metabolism studies to track and quantify drug candidates and their metabolites with high precision.
• Food Safety & Contaminant Analysis: Enables the precise detection and quantification of heterocyclic aromatic amines (HAAs), which are potential carcinogens formed in cooked meats, ensuring compliance with food safety regulations.
• Toxicological & Biomarker Research: Facilitates studies on exposure biomarkers and DNA adduct formation related to HAA exposure in environmental and occupational health research.
• Reference Standard for Method Development: Serves as a critical calibrant and validation standard for developing and optimizing new analytical methods in regulatory and contract testing laboratories.

Basic Information

Product Name	2-Amino-3,7,8-Trimethyl-3H-Imidazo[4,5-F]Quinoxaline-D3
CAS No.	1189421-19-9
Molecular Formula	C12H9D3N5
Molecular Weight	217.26 g/mol
Synonyms	2-Amino-3,7,8-trimethylimidazo[4,5-f]quinoxaline-d3; 4,8-Dimethyl-3,7,9-triaza-cyclopenta[a]naphthalen-2-amine-d3; 2-Amino-3,7,8-trimethyl-3H-imidazo[4,5-f]quinoxaline (trideuterated); 4,8-Dimethylimidazo[4,5-f]quinoxalin-2-amine-d3; Deuterated MeIQx; [D3]-2-Amino-3,7,8-trimethylimidazo[4,5-f]quinoxaline; 2-Amino-3,7,8-trimethyl-3H-imidazo[4,5-f]quinoxaline (methyl-d3); Internal Standard for MeIQx
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-3,7,8-Trimethyl-3H-Imidazo[4,5-F]Quinoxaline-D3 is manufactured and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity to meet the exacting demands of analytical reference standard applications. Comprehensive testing includes identity confirmation, assay determination, and verification of deuterium incorporation. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results for traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage at 2-8°C. Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D3)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.