Description

5-(5-Chloro-Thiophen-2-Yl)-2H-Pyrazole-3-Carboxylic Acid is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines a chlorinated thiophene moiety with a pyrazole carboxylic acid functional group, enabling precise chemical modifications. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and fungicides, leveraging its heterocyclic structure for bioactivity.
• Material Science Research: Serves as a precursor for functionalized polymers or organic electronic materials due to its conjugated system.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized compounds for clients.

Basic Information

Product Name	5-(5-Chloro-Thiophen-2-Yl)-2H-Pyrazole-3-Carboxylic Acid
CAS No.	1188375-25-8
Molecular Formula	C8H5ClN2O2S
Molecular Weight	228.65 g/mol
Synonyms	5-(5-Chlorothiophen-2-yl)-1H-pyrazole-3-carboxylic acid; 5-(5-Chloro-2-thienyl)-1H-pyrazole-3-carboxylic acid; 2H-Pyrazole-3-carboxylic acid, 5-(5-chloro-2-thienyl)-; 1188375-25-8; 5-(5-Chlorothiophen-2-yl)-2H-pyrazole-3-carboxylic acid; 5-(5-Chloro-thiophen-2-yl)-1H-pyrazole-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 5-(5-Chloro-Thiophen-2-Yl)-2H-Pyrazole-3-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.