Description

3-Amino-2-Oxazolidinone D4 is a deuterated isotopologue of a key oxazolidinone derivative, serving as a critical stable isotope-labeled internal standard for precise analytical quantification. This high-purity compound is essential for ensuring accuracy and reliability in sensitive mass spectrometry-based methods, particularly in regulated environments. It is primarily required by pharmaceutical research and development laboratories, contract research organizations (CROs), and analytical service providers for pharmacokinetic studies, metabolism research, and bioanalytical method development.

Application

• Internal Standard for LC-MS/MS: Used as a quantitative reference standard in Liquid Chromatography-Tandem Mass Spectrometry for drug and metabolite analysis.
• Pharmacokinetic/Pharmacodynamic (PK/PD) Studies: Enables accurate measurement of drug concentration in biological matrices (plasma, serum, urine) over time.
• Metabolite Identification and Profiling: Aids in the detection and structural elucidation of drug metabolites in complex biological samples.
• Bioanalytical Method Development and Validation: Critical for developing robust, reproducible, and GLP-compliant analytical methods.
• Drug Metabolism and Disposition (DMPK) Research: Supports studies on absorption, distribution, metabolism, and excretion (ADME) of pharmaceutical compounds.
• Clinical Trial Sample Analysis: Ensures data integrity and regulatory compliance in the analysis of samples from human clinical trials.
• Veterinary Drug Residue Testing: Applied in food safety testing to monitor for veterinary drug residues in animal-derived products.

Basic Information

Item	Detail
Product Name	3-Amino-2-Oxazolidinone D4
CAS No.	1188331-23-8
Molecular Formula	C₃H₂D₄N₂O₂
Molecular Weight	~106.11 g/mol
Synonyms	3-Amino-2-oxazolidinone-d4; 2-Oxazolidinone, 3-amino-, D4; Deuterated 3-Amino-2-oxazolidinone; [2H4]-3-Amino-2-oxazolidinone; AOZ D4; 3-Amino-1,3-oxazolidin-2-one-d4; (Aminooxazolidinone)-d4; Stable Isotope Labeled 3-AOZ
EINECS	Contact for details

Quality Control

Every batch of 3-Amino-2-Oxazolidinone D4 is produced and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity, with comprehensive testing including HPLC for chemical purity, NMR and MS for structural and isotopic confirmation, and residual solvent analysis. Certificates of Analysis (COA) are provided with each shipment, detailing batch-specific results. Our quality commitment supports compliance with GMP and ISO 9001 standards for research and regulatory applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.