Description

2-(1,2,3,4-Tetrahydroisoquinolin-3-Yl)Acetic Acid Hydrochloride is a high-purity organic salt compound, serving as a critical building block in advanced pharmaceutical synthesis. Its value lies in its role as a versatile intermediate for constructing complex nitrogen-containing heterocycles, which are core structures in many active pharmaceutical ingredients. This product is essential for research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates targeting neurological and cardiovascular diseases.
• Agrochemical Research: Building block for developing new herbicides and pesticides with specific biological activity.
• Fine Chemical Synthesis: Used in the preparation of complex molecules for material science and specialty chemistry applications.
• Academic & Contract Research: Valuable reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in academic and CRO settings.
• Peptidomimetic Development: Serves as a constrained scaffold in the design of peptide analogs and enzyme inhibitors.

Basic Information

Product Name	2-(1,2,3,4-Tetrahydroisoquinolin-3-Yl)Acetic Acid Hydrochloride
CAS No.	1188265-30-6
Molecular Formula	C₁₁H₁₄ClNO₂
Molecular Weight	227.69 g/mol
Synonyms	2-(1,2,3,4-Tetrahydro-3-isoquinolinyl)acetic acid hydrochloride; 2-(3,4-Dihydro-1H-isoquinolin-3-yl)acetic acid hydrochloride; 2-(1,2,3,4-Tetrahydroisoquinolin-3-yl)ethanoic acid hydrochloride; TIQAA-HCl; 1188265-30-6; 2-(1,2,3,4-Tetrahydroisoquinolin-3-yl)acetic acid HCl salt
EINECS	Contact for details

Quality Control

Our 2-(1,2,3,4-Tetrahydroisoquinolin-3-Yl)Acetic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.