Description

4,7-Difluorol-2(3H)-Benzothiazolone is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, particularly those targeting specific biological pathways. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules with tailored properties.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), especially in drug discovery programs for central nervous system (CNS) and anti-infective agents.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the fluorine atoms for enhanced bioactivity and environmental stability.
• Material Science Precursor: Serves as a monomer or precursor for synthesizing specialty polymers, dyes, and organic electronic materials with unique optical or electronic properties.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways in research settings.
• Organic Synthesis Reagent: Utilized in various name reactions and coupling protocols to introduce the benzothiazolone scaffold into more complex molecular architectures.

Basic Information

Product Name	4,7-Difluorol-2(3H)-Benzothiazolone
CAS No.	1188043-35-7
Molecular Formula	C7H3F2NOS
Molecular Weight	187.17 g/mol
Synonyms	4,7-Difluoro-2-benzothiazolinone; 4,7-Difluoro-2(3H)-benzothiazolone; 2(3H)-Benzothiazolone, 4,7-difluoro-; 4,7-Difluoro-1,3-benzothiazol-2(3H)-one; 4,7-Difluoro-2-hydroxybenzothiazole; 4,7-Difluoro-2-oxo-2,3-dihydro-1,3-benzothiazole
EINECS	Contact for details

Quality Control

Our 4,7-Difluorol-2(3H)-Benzothiazolone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our commitment to quality supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent any potential moisture uptake. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.