Description

1,2,3,4-Tetrahydro-4-(1-Hydroxycyclohexyl)-2-Methyl-7-Isoquinolinol CAS NO 1187948-72-6 is a high-purity, synthetically derived isoquinoline derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for research and development. It is primarily sought after by pharmaceutical companies and contract research organizations (CROs) engaged in the discovery and development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates targeting neurological and metabolic disorders.
• Organic Synthesis Building Block: Used in research laboratories for constructing novel heterocyclic compounds and exploring new chemical spaces.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to optimize the biological activity of lead compounds.
• Chemical Reference Standard: Serves as a high-purity analytical standard for method development and quality control in API manufacturing.
• Academic Research: Utilized in university and institutional research for studying synthetic methodologies and reaction mechanisms.

Basic Information

Product Name	1,2,3,4-Tetrahydro-4-(1-Hydroxycyclohexyl)-2-Methyl-7-Isoquinolinol
CAS No.	1187948-72-6
Molecular Formula	C₁₆H₂₃NO₂
Molecular Weight	261.36 g/mol
Synonyms	4-(1-Hydroxycyclohexyl)-2-methyl-1,2,3,4-tetrahydro-7-isoquinolinol; 2-Methyl-4-(1-hydroxycyclohexyl)-1,2,3,4-tetrahydroisoquinolin-7-ol; 7-Isoquinolinol, 1,2,3,4-tetrahydro-4-(1-hydroxycyclohexyl)-2-methyl-; THIQ derivative; Isoquinoline alkaloid intermediate
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydro-4-(1-Hydroxycyclohexyl)-2-Methyl-7-Isoquinolinol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.