Description

(S)-(1,2,3,4-Tetrahydro-Isoquinolin-3-Ylmethyl)-Carbamic Acid tert-Butyl Ester is a high-purity chiral building block and Boc-protected intermediate of significant value in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. Pharmaceutical R&D laboratories and fine chemical manufacturers need it for the synthesis of potential drug candidates, especially those targeting neurological and cardiovascular pathways.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents.
• API Synthesis: Used in the construction of complex molecules for potential drug candidates in neurological and cardiovascular disease research.
• Asymmetric Synthesis: Serves as a valuable building block in stereoselective synthesis due to its defined (S)-configuration.
• Peptidomimetics Research: Employed in the design and synthesis of peptide-like compounds for medicinal chemistry applications.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological systems and target validation.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs engaged in custom chemical synthesis projects.

Basic Information

Product Name	(S)-(1,2,3,4-Tetrahydro-Isoquinolin-3-Ylmethyl)-Carbamic Acid tert-Butyl Ester
CAS No.	1187933-37-4
Molecular Formula	C16H24N2O2
Molecular Weight	276.38 g/mol
Synonyms	(S)-tert-Butyl (1,2,3,4-tetrahydroisoquinolin-3-ylmethyl)carbamate; (S)-N-Boc-1,2,3,4-tetrahydro-3-isoquinolinemethanamine; (S)-3-(Aminomethyl)-1,2,3,4-tetrahydroisoquinoline, N-Boc derivative; Boc-THIQ-3-CH2NH2 (S-isomer); (S)-1,2,3,4-Tetrahydroisoquinoline-3-methanamine, N-Boc-; (S)-N-(tert-Butoxycarbonyl)-1,2,3,4-tetrahydro-3-isoquinolinemethanamine; (S)-3-((tert-Butoxycarbonylamino)methyl)-1,2,3,4-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our (S)-(1,2,3,4-Tetrahydro-Isoquinolin-3-Ylmethyl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with high-purity standards for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.