Description

4-Cyano-2,3-Dihydro-1H-Indole Hydrochloride is a high-purity, versatile pharmaceutical intermediate and building block. This compound is critical for the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to optimize lead compounds.
• Agrochemical Synthesis: Serves as a precursor in the development of new pesticides and herbicides with specific biological activity.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and advanced intermediates at various scales.

Basic Information

Product Name	4-Cyano-2,3-Dihydro-1H-Indole Hydrochloride
CAS No.	1187933-20-5
Molecular Formula	C9H9ClN2
Molecular Weight	180.63 g/mol
Synonyms	4-Cyanoindoline Hydrochloride; 1H-Indole-4-carbonitrile, 2,3-dihydro-, hydrochloride; 2,3-Dihydro-1H-indole-4-carbonitrile hydrochloride; 4-CN-indoline HCl; Indoline-4-carbonitrile hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Cyano-2,3-Dihydro-1H-Indole Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from moisture to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.