Description

[2-(3-Bromo-Isoxazol-5-Yl)-Ethyl]-Carbamic Acid tert-Butyl Ester is a specialized chemical building block featuring a brominated isoxazole heterocycle protected by a Boc (tert-butoxycarbonyl) group. This compound is valued for its dual functionality, serving as a versatile intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the life sciences industry for constructing novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, leveraging the bioactive isoxazole scaffold.
• Chemical Biology Probe Development: Serves as a precursor for synthesizing molecular probes to study enzyme function and biological pathways.
• Peptidomimetics & PROTACs: The Boc-protected amine is instrumental in constructing peptide-like molecules and Proteolysis-Targeting Chimeras (PROTACs) for targeted protein degradation.
• Material Science Research: Potential building block for novel polymers or organic electronic materials with specific optoelectronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	[2-(3-Bromo-Isoxazol-5-Yl)-Ethyl]-Carbamic Acid tert-Butyl Ester
CAS No.	1187932-88-2
Molecular Formula	C10H15BrN2O3
Molecular Weight	291.15 g/mol
Synonyms	tert-Butyl N-[2-(3-bromo-1,2-oxazol-5-yl)ethyl]carbamate; Boc-2-(3-Bromo-isoxazol-5-yl)-ethylamine; 5-[2-[(tert-Butoxycarbonyl)amino]ethyl]-3-bromoisoxazole; N-Boc-2-(3-bromoisoxazol-5-yl)ethanamine; 2-(3-Bromo-isoxazol-5-yl)-ethyl-carbamic acid tert-butyl ester; 3-Bromo-5-(2-((tert-butoxycarbonyl)amino)ethyl)isoxazole; Boc-AEA(Br-Isoxazole); 1187932-88-2
EINECS	Contact for details

Quality Control

Our [2-(3-Bromo-Isoxazol-5-Yl)-Ethyl]-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment. We support development and commercial projects with material suitable for research use and can offer grades aligned with cGMP guidelines for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.