Description

3-Chloro-1-Pyridin-4-Ylmethyl-1H-Indazole Hydrochloride is a high-purity, non-nucleoside pharmaceutical intermediate with significant synthetic utility. Its core value lies in its role as a critical building block for the research and development of novel, biologically active compounds, particularly in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology industries focused on creating new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for targeted therapies.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Used in the development of assay systems and as a reference standard for pharmacological studies.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to introduce the indazole-pyridine pharmacophore into target molecules.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.
• Academic Research: Utilized in university and institutional labs for exploratory research in heterocyclic chemistry and bioorganic chemistry.

Basic Information

Product Name	3-Chloro-1-Pyridin-4-Ylmethyl-1H-Indazole Hydrochloride
CAS No.	1187932-80-4
Molecular Formula	C14H12Cl2N3 • HCl
Molecular Weight	324.63 g/mol (Free base: 288.17 g/mol)
Synonyms	3-Chloro-1-[(pyridin-4-yl)methyl]-1H-indazole hydrochloride; 1H-Indazole, 3-chloro-1-[(4-pyridinyl)methyl]-, hydrochloride (1:1); 3-Chloro-1-(4-pyridylmethyl)indazole hydrochloride; 3-Chloro-1-(pyridin-4-ylmethyl)-1H-indazole HCl; 1187932-80-4; CAS 1187932-80-4
EINECS	Contact for details

Quality Control

Our 3-Chloro-1-Pyridin-4-Ylmethyl-1H-Indazole Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.