Description

6-Nitro-2,3-dihydro-1H-indole hydrochloride is a high-purity chemical intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a versatile building block for constructing complex heterocyclic frameworks, particularly in pharmaceutical research and development. This compound is essential for chemists and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its nitro-substituted indoline structure.
• Organic Synthesis: Serves as a versatile precursor for the preparation of more complex fused-ring systems and functionalized indoles.
• Material Science Research: Potential intermediate in the synthesis of organic semiconductors, dyes, and photochromic materials.
• Biochemical Probe Development: Used in medicinal chemistry to create molecular probes for studying biological pathways and enzyme inhibition.

Basic Information

Product Name	6-Nitro-2,3-dihydro-1H-indole hydrochloride
CAS No.	1187929-53-8
Molecular Formula	C8H9N2O2·HCl
Molecular Weight	216.63 g/mol
Synonyms	6-Nitroindoline hydrochloride; 2,3-Dihydro-6-nitro-1H-indole hydrochloride; 1H-Indole, 2,3-dihydro-6-nitro-, hydrochloride; 6-Nitro-2,3-dihydro-1H-indole HCl; 6-Nitroindoline HCl; 6-Nitro-2,3-dihydroindole hydrochloride
EINECS	Contact for details

Quality Control

Our 6-Nitro-2,3-dihydro-1H-indole hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed when not in use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.