Description

4-Iodoindoline Hydrochloride is a key halogenated indoline derivative used as a versatile synthetic intermediate in advanced organic chemistry. Its value lies in providing a functionalized scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active compounds and exploring new synthetic pathways.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging the indoline core for biological activity.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular probes to study biological pathways and protein functions.
• Material Science Research: Employed in the synthesis of organic electronic materials and advanced polymers where the indoline structure is beneficial.
• Academic & Contract Research: A valuable reagent for methodology development and complex molecule synthesis in university and CRO laboratory settings.
• Scale-up Process Development: Used in optimizing synthetic routes from milligram to kilogram scale for potential commercial production of target molecules.

Basic Information

Product Name	4-Iodoindoline Hydrochloride
CAS No.	1187929-37-8
Molecular Formula	C8H9IN2·HCl
Molecular Weight	296.53 g/mol
Synonyms	4-Iodo-2,3-dihydro-1H-indole Hydrochloride; 1H-Indole, 4-iodo-2,3-dihydro-, hydrochloride; Indoline, 4-iodo-, hydrochloride; 4-Iodoindoline HCl; 4-Iodo-2,3-dihydroindole Hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Iodoindoline Hydrochloride is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure full traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.