Description

Isoquinolin-8-Ylamine Dihydrochloride CAS NO 1187929-16-3 is a high-purity, dihydrochloride salt derivative of an isoquinoline-based primary amine, serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a stable, readily handled form of a key aromatic amine intermediate for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries, where it is utilized in the development of active pharmaceutical ingredients (APIs), functional ligands, and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the isoquinoline scaffold's bioactivity.
• Ligand Synthesis: Serves as a starting material for creating chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Organic Electronic Materials: A building block for synthesizing conjugated molecules and polymers for applications in OLEDs and semiconductors.
• Chemical Biology Probes: Utilized to develop fluorescent tags or affinity probes for studying biological processes and protein interactions.
• Academic & R&D: A versatile reagent for methodological studies in organic chemistry and the exploration of new synthetic pathways.

Basic Information

Product Name	Isoquinolin-8-Ylamine Dihydrochloride
CAS No.	1187929-16-3
Molecular Formula	C9H11Cl2N2
Molecular Weight	218.10 g/mol
Synonyms	8-Aminoisoquinoline Dihydrochloride; 8-Isoquinolinamine Dihydrochloride; 1,3-Dihydro-2H-isoindole-8-amine Dihydrochloride; Isoquinolin-8-amine Hydrochloride (1:2); 8-Isoquinolylamine Dihydrochloride; 1187929-16-3; 8-Aminoisoquinoline, 2HCl
EINECS	Contact for details

Quality Control

Every batch of Isoquinolin-8-Ylamine Dihydrochloride is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing results from HPLC, NMR, and other relevant analytical techniques. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0% (Anhydrous Basis)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.