Description

1-Ethyl-2,3-Dihydro-1H-Indole-6-Carbonitrile Hydrochloride is a high-purity organic salt of significant interest in advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of novel active molecules. It is primarily utilized by research institutions and industrial manufacturers in the life sciences sector for applications in medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold or building block for designing and optimizing new chemical entities with potential biological activity.
• Agrochemical Development: Serves as an intermediate in the research and production of advanced crop protection agents and pesticides.
• Organic Synthesis: Employed in academic and industrial laboratories for constructing complex heterocyclic compounds and fine chemicals.
• Biochemical Research: Potential use as a tool compound or probe in studying biological pathways and enzyme interactions.

Basic Information

Product Name	1-Ethyl-2,3-Dihydro-1H-Indole-6-Carbonitrile Hydrochloride
CAS No.	1187928-73-9
Molecular Formula	C11H13N2·HCl
Molecular Weight	208.70 g/mol (Free base: 172.23 g/mol)
Synonyms	6-Cyano-1-ethylindoline hydrochloride; 1-Ethyl-2,3-dihydro-6-cyanoindole hydrochloride; 1-Ethyl-6-cyanoindoline hydrochloride; 1-Ethylindoline-6-carbonitrile hydrochloride; 1187928-73-9; 1-Ethyl-1,2,3,4-tetrahydro-6-cyanoquinoline hydrochloride (incorrect but common misnomer); 1-Ethyl-2,3-dihydro-1H-indole-6-carbonitrile HCl
EINECS	Contact for details

Quality Control

Our 1-Ethyl-2,3-Dihydro-1H-Indole-6-Carbonitrile Hydrochloride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.