Description

3-Piperidin-4-Ylmethyl-Isoquinoline Dihydrochloride is a high-purity, advanced pharmaceutical intermediate and research chemical. This compound is of significant interest for its role as a key building block in the synthesis of novel bioactive molecules, particularly in central nervous system (CNS) and oncology research. It is primarily utilized by pharmaceutical R&D departments, biotechnology companies, and academic research institutions engaged in medicinal chemistry and drug discovery programs. The dihydrochloride salt form enhances its stability and solubility for experimental use.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates targeting specific receptors.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies in academic and industrial labs.
• Biochemical Tool Compound: Employed in vitro and in vivo to study biological pathways and validate novel therapeutic targets.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Library Synthesis: Used in the generation of diverse compound libraries for high-throughput screening (HTS) campaigns.

Basic Information

Product Name	3-Piperidin-4-Ylmethyl-Isoquinoline Dihydrochloride
CAS No.	1187928-64-8
Molecular Formula	C₁₆H₂₀N₂·2HCl
Molecular Weight	313.26 g/mol (Free base: 240.35 g/mol)
Synonyms	3-((Piperidin-4-yl)methyl)isoquinoline dihydrochloride; 3-(4-Piperidinylmethyl)isoquinoline dihydrochloride; 3-Piperidin-4-ylmethylisoquinoline dihydrochloride; Isoquinoline, 3-[(4-piperidinyl)methyl]-, dihydrochloride; 1187928-64-8; 3-(Piperidin-4-ylmethyl)isoquinoline 2HCl
EINECS	Contact for details

Quality Control

Our 3-Piperidin-4-Ylmethyl-Isoquinoline Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.