Description

5-Methoxycarbonyl-2,3-Dihydro-1H-Indole Hydrochloride is a high-purity indole derivative, serving as a critical advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its core value lies in enabling the development of complex molecules, particularly for research and production in life sciences. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing indole-based compound libraries for high-throughput screening (HTS).
• Agrochemical Synthesis: Building block for developing new active ingredients in crop protection products.
• Organic Synthesis: Fundamental reagent for constructing complex heterocyclic structures in academic and industrial R&D settings.
• Chemical Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	5-Methoxycarbonyl-2,3-Dihydro-1H-Indole Hydrochloride
CAS No.	1187928-10-4
Molecular Formula	C11H12ClNO2
Molecular Weight	225.67 g/mol
Synonyms	Methyl 2,3-dihydro-1H-indole-5-carboxylate hydrochloride; 1H-Indole-5-carboxylic acid, 2,3-dihydro-, methyl ester, hydrochloride; 5-(Methoxycarbonyl)indoline hydrochloride; Indoline-5-carboxylic acid methyl ester hydrochloride; 5-Carbomethoxyindoline HCl
EINECS	Contact for details

Quality Control

Our 5-Methoxycarbonyl-2,3-Dihydro-1H-Indole Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.