Description

6-Methoxycarbonyl-2,3-Dihydro-1H-Indole Hydrochloride is a high-purity organic salt building block, essential for advanced pharmaceutical synthesis and fine chemical research. Its core value lies in its role as a versatile intermediate for constructing complex heterocyclic molecules, enabling the development of novel active pharmaceutical ingredients (APIs). This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new therapeutic agents and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex indole-based drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of novel herbicides and fungicides that leverage the indole scaffold for biological activity.
• Organic Synthesis Building Block: Serves as a versatile starting material for constructing fused heterocyclic systems in academic and industrial research laboratories.
• Material Science: Potential intermediate for the synthesis of organic semiconductors and advanced polymers with specific electronic properties.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	6-Methoxycarbonyl-2,3-Dihydro-1H-Indole Hydrochloride
CAS No.	1187928-05-7
Molecular Formula	C11H12ClNO2
Molecular Weight	225.67 g/mol
Synonyms	Methyl 2,3-dihydro-1H-indole-6-carboxylate hydrochloride; 1H-Indole-6-carboxylic acid, 2,3-dihydro-, methyl ester, hydrochloride; 6-(Methoxycarbonyl)-2,3-dihydro-1H-indole hydrochloride; Methyl 1,2,3,4-tetrahydro-6-carbazolecarboxylate hydrochloride (incorrect but common misnomer); 6-Carbomethoxy-2,3-dihydroindole HCl
EINECS	Contact for details

Quality Control

Our 6-Methoxycarbonyl-2,3-Dihydro-1H-Indole Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, and we support customer audits and regulatory documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.