Description

4-Iodo-1-(Pyridin-4-Ylmethyl)Pyrazole is a specialized heterocyclic building block featuring a pyrazole core functionalized with an iodine atom and a pyridinylmethyl group. This compound is of significant value in medicinal chemistry and materials science due to its versatile reactivity, particularly the iodine substituent which enables efficient cross-coupling reactions. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active compounds and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its halogenated structure for structure-activity relationship (SAR) studies.
• Material Science: Serves as a building block for creating functional organic materials, such as ligands for metal-organic frameworks (MOFs) or organic electronic components.
• Chemical Synthesis: The iodine atom is an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create more complex molecular architectures.
• Bioconjugation & Probe Development: Can be utilized in the design of chemical probes and bioconjugation reagents for biochemical and diagnostic applications.

Basic Information

Product Name	4-Iodo-1-(Pyridin-4-Ylmethyl)Pyrazole
CAS No.	1187385-85-8
Molecular Formula	C9H8IN3
Molecular Weight	285.09 g/mol
Synonyms	1-[(Pyridin-4-yl)methyl]-4-iodo-1H-pyrazole; 4-Iodo-1-(4-pyridylmethyl)pyrazole; 1H-Pyrazole, 4-iodo-1-[(4-pyridinyl)methyl]-; 4-Iodo-1-(pyridin-4-ylmethyl)-1H-pyrazole; 1-(Pyridin-4-ylmethyl)-4-iodopyrazole; 4-Iodo-1-(4-pyridinylmethyl)pyrazole; 4-Iodo-1-(4-pyridylmethyl)-1H-pyrazole
EINECS	Contact for details

Quality Control

Our 4-Iodo-1-(Pyridin-4-Ylmethyl)Pyrazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.