Description

5-Nitro-6-(Trifluoromethyl)-1H-Indazole is a high-value, multi-functional heterocyclic building block featuring both nitro and trifluoromethyl substituents. This compound is critical for medicinal chemistry and advanced materials research, where its unique electronic and steric properties enable the development of novel active compounds. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of new drug candidates and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, receptor antagonists, and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing trifluoromethyl group.
• Material Science: Serves as a precursor for organic electronic materials, such as OLED emitters or charge-transport layers.
• Chemical Biology: Employed as a probe or labeling agent in biochemical assays and diagnostic development.
• Academic & Contract Research: Essential for exploratory synthetic chemistry and methodology development in university and CRO laboratories.

Basic Information

Product Name	5-Nitro-6-(Trifluoromethyl)-1H-Indazole
CAS No.	1187211-61-5
Molecular Formula	C8H4F3N3O2
Molecular Weight	231.14 g/mol
Synonyms	1H-Indazole, 5-nitro-6-(trifluoromethyl)-; 5-Nitro-6-(trifluoromethyl)indazole; 6-(Trifluoromethyl)-5-nitro-1H-indazole; 5-Nitro-6-trifluoromethylindazole; 1187211-61-5
EINECS	Contact for details

Quality Control

Our 5-Nitro-6-(Trifluoromethyl)-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to ensure stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.