Description

5,7-Di-Fluoro-1,2,3,4-Tetrahydroisoquinoline Hcl is a high-purity, fluorinated tetrahydroisoquinoline derivative, a crucial building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where its unique fluorine-substituted structure imparts desirable metabolic stability and bioavailability. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for drug discovery and process development programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy.
• Chemical Biology: Used as a molecular scaffold or probe in medicinal chemistry for structure-activity relationship (SAR) studies.
• Fluorinated Compound Synthesis: A valuable starting material for introducing the 5,7-difluoro-tetrahydroisoquinoline moiety into more complex molecules.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process optimization.

Basic Information

Product Name	5,7-Di-Fluoro-1,2,3,4-Tetrahydroisoquinoline Hydrochloride
CAS No.	1187174-14-6
Molecular Formula	C9H9F2N•HCl
Molecular Weight	205.63 g/mol
Synonyms	5,7-Difluoro-1,2,3,4-tetrahydroisoquinoline hydrochloride; 1,2,3,4-Tetrahydro-5,7-difluoroisoquinoline hydrochloride; 5,7-Difluoro-3,4-dihydro-1H-isoquinoline hydrochloride; 5,7-Difluoro-THIQ HCl; 1187174-14-6; 5,7-Difluoro-1,2,3,4-tetrahydroisoquinoline HCl
EINECS	Contact for details

Quality Control

Our 5,7-Di-Fluoro-1,2,3,4-Tetrahydroisoquinoline Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.