Description

4-(4-Cyanobenzoyl)Isoquinoline is a high-purity, advanced pharmaceutical intermediate characterized by its distinct isoquinoline core functionalized with a cyanobenzoyl group. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and receptor modulators.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes to construct complex heterocyclic frameworks.
• Biochemical Tool Compound: Utilized in biochemical assays and as a reference standard for analytical method development.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Used in university laboratories for investigating novel organic reactions and catalytic processes.

Basic Information

Product Name	4-(4-Cyanobenzoyl)Isoquinoline
CAS No.	1187167-84-5
Molecular Formula	C17H10N2O
Molecular Weight	258.28 g/mol
Synonyms	4-(4-Cyanobenzoyl)isoquinoline; 4-Isoquinolinyl(4-cyanophenyl)methanone; (4-Cyanophenyl)(isoquinolin-4-yl)methanone; 4-(4-Cyanobenzoyl)isoquinoline; 1187167-84-5; 4-Cyanobenzoyl isoquinoline; 4-(4-Cyanobenzoyl)-isoquinoline
EINECS	Contact for details

Quality Control

Our 4-(4-Cyanobenzoyl)Isoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and adherence to ICH Q7 guidelines ensure the material is suitable for use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.