Description

4-(3-Fluorobenzoyl)Isoquinoline is a specialized fluorinated isoquinoline derivative, a high-value building block in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which combines a fluorinated benzoyl moiety with the isoquinoline heterocycle, enabling precise modulation of electronic and steric properties in target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially in kinase inhibitor research and central nervous system (CNS) targeted therapies.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, where the fluorine atom enhances bioavailability and metabolic stability.
• Material Science: Serves as a building block for creating advanced organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probe Development: Utilized in designing fluorescent tags or molecular probes for studying biological processes due to the isoquinoline fluorophore.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and exploring novel heterocyclic chemistry.

Basic Information

Product Name	4-(3-Fluorobenzoyl)Isoquinoline
CAS No.	1187166-24-0
Molecular Formula	C₁₆H₁₀FNO
Molecular Weight	251.26 g/mol
Synonyms	4-(3-Fluorobenzoyl)isoquinoline; 3-Fluoro-4-isoquinolinyl phenyl ketone; (3-Fluorophenyl)(isoquinolin-4-yl)methanone; 4-(3-Fluorobenzoyl)isoquinoline; 1187166-24-0; 4-Isoquinolinyl 3-fluorophenyl ketone
EINECS	Contact for details

Quality Control

Our 4-(3-Fluorobenzoyl)Isoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container sealed to minimize contact with moisture and atmospheric oxygen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.