Description

4-(5-Methyl-Pyridin-2-Yl)-Isoquinoline is a high-purity, advanced heterocyclic building block and pharmaceutical intermediate of significant commercial interest. Its unique fused-ring structure makes it a valuable scaffold in medicinal chemistry for the development of novel therapeutic agents. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in drug discovery, particularly for targeting kinase-related pathways and other biological processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) for oncology, neurology, and anti-inflammatory applications.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and high-throughput screening in drug discovery programs.
• Kinase Inhibitor Development: Used in the research and development of potent and selective kinase inhibitors due to its privileged heterocyclic structure.
• Organic Synthesis Building Block: Employed in complex multi-step organic syntheses to construct more elaborate molecular architectures.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and pesticides.
• Material Science: Investigated as a precursor for organic electronic materials, such as ligands in coordination polymers or OLED components.

Basic Information

Product Name	4-(5-Methyl-Pyridin-2-Yl)-Isoquinoline
CAS No.	1187164-15-3
Molecular Formula	C15H12N2
Molecular Weight	220.27 g/mol
Synonyms	4-(5-Methyl-2-pyridinyl)isoquinoline; 4-(5-Methylpyridin-2-yl)isoquinoline; Isoquinoline, 4-(5-methyl-2-pyridinyl)-; 2-(Isoquinolin-4-yl)-5-methylpyridine; 4-(5-Methyl-2-pyridyl)isoquinoline
EINECS	Contact for details

Quality Control

Our 4-(5-Methyl-Pyridin-2-Yl)-Isoquinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and internal quality standards. Custom synthesis and purification to meet specific research-grade or cGMP standards are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.