Description

Ethyl 5-(Isoquinolin-4-Yl)Thiophene-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a unique heterocyclic scaffold that combines isoquinoline and thiophene motifs. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel small-molecule drug candidates targeting a range of therapeutic areas. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries seeking to explore new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential active pharmaceutical ingredients (APIs) for oncology, CNS disorders, and anti-infective therapies.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to develop novel drug candidates with improved potency and pharmacokinetic properties.
• Chemical Biology Probes: Employed in the development of molecular probes to study biological pathways and protein functions due to its distinctive heterocyclic structure.
• Agrochemical Research: Acts as a precursor in the development of new crop protection agents and pesticides.
• Material Science: Investigated as a monomer or precursor for functional organic materials, such as organic semiconductors or ligands for catalysis.

Basic Information

Product Name	Ethyl 5-(Isoquinolin-4-Yl)Thiophene-2-Carboxylate
CAS No.	1187164-06-2
Molecular Formula	C₁₆H₁₃NO₂S
Molecular Weight	283.35 g/mol
Synonyms	Ethyl 5-(4-isoquinolyl)thiophene-2-carboxylate; 5-(Isoquinolin-4-yl)thiophene-2-carboxylic acid ethyl ester; 2-Thiophenecarboxylic acid, 5-(4-isoquinolinyl)-, ethyl ester; 1187164-06-2; AKOS006361583; CS-0417926; FT-0774837; NS00093827
EINECS	Contact for details

Quality Control

Every batch of Ethyl 5-(Isoquinolin-4-Yl)Thiophene-2-Carboxylate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and analytical methods is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.