Description

5-(6-Chloro-Pyridin-3-Yl)-Thiophene-2-Carboxylic Acid Ethyl Ester is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound matters for its critical role in the synthesis of complex molecules, particularly in medicinal chemistry and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation pesticides and herbicides, leveraging its bifunctional heterocyclic structure.
• Material Science Research: Serves as a precursor for organic electronic materials and functional polymers due to the thiophene moiety.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for target identification and validation studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client projects.
• Academic & Institutional Research: Used in university and government labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	5-(6-Chloro-Pyridin-3-Yl)-Thiophene-2-Carboxylic Acid Ethyl Ester
CAS No.	1187163-71-8
Molecular Formula	C13H11ClN2O2S
Molecular Weight	294.75 g/mol
Synonyms	Ethyl 5-(6-chloropyridin-3-yl)thiophene-2-carboxylate; 5-(6-Chloro-3-pyridyl)thiophene-2-carboxylic acid ethyl ester; 2-Thiophenecarboxylic acid, 5-(6-chloro-3-pyridinyl)-, ethyl ester; 1187163-71-8; Ethyl 5-(6-chloro-3-pyridinyl)-2-thiophenecarboxylate; 5-(6-Chloropyridin-3-yl)thiophene-2-carboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our 5-(6-Chloro-Pyridin-3-Yl)-Thiophene-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.