Description

3-Bromo-5-Fluoroindole is a high-purity halogenated indole derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in providing a versatile, functionalized scaffold for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the halogenated indole core.
• Material Science: Serves as a precursor for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-rich indole structure.
• Chemical Biology & Proteomics: Employed as a probe or labeling reagent in biochemical research to study protein interactions and enzyme mechanisms.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry laboratories and for custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Product Name	3-Bromo-5-Fluoroindole
CAS No.	1186663-46-6
Molecular Formula	C8H5BrFN
Molecular Weight	214.04 g/mol
Synonyms	5-Fluoro-3-bromoindole; 3-Bromo-5-fluoro-1H-indole; 1H-Indole, 3-bromo-5-fluoro-; 5-Fluoro-3-bromo-1H-indole; 3-Bromo-5-fluoroindole; 1186663-46-6 (CAS)
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Fluoroindole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.