Description

Methyl 3-Bromo-1-Methylindole-6-Carboxylate is a high-purity, synthetically valuable brominated indole derivative. This compound serves as a critical advanced pharmaceutical intermediate and versatile building block in organic synthesis, enabling the construction of complex molecular architectures. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders and oncology.
• Agrochemical Research: Building block for developing new generation herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Reagent: Used in cross-coupling reactions (e.g., Suzuki, Stille) and as a substrate for further functionalization of the indole core.
• Material Science: Potential monomer or precursor for creating specialty polymers and organic electronic materials.
• Academic & Contract Research: Essential for methodological studies and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	Methyl 3-Bromo-1-Methylindole-6-Carboxylate
CAS No.	1186663-45-5
Molecular Formula	C11H10BrNO2
Molecular Weight	268.11 g/mol
Synonyms	Methyl 3-bromo-1-methyl-1H-indole-6-carboxylate; 6-Carbomethoxy-3-bromo-1-methylindole; 1-Methyl-3-bromoindole-6-carboxylic acid methyl ester; 3-Bromo-1-methyl-1H-indole-6-carboxylic acid methyl ester; 3-Bromo-1-methylindole-6-carboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Bromo-1-Methylindole-6-Carboxylate adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support cGMP compliance for advanced intermediates and can provide material for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Any single unknown impurity	≤1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.