Description

5-Chloro-6-(Trifluoromethyl)-1H-Indole is a high-value, multi-functional indole derivative distinguished by its unique halogenated and trifluoromethylated structure. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block for complex organic synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in oncology, CNS disorders, and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the biological activity of the indole core and fluorine atoms.
• Organic Light-Emitting Diodes (OLEDs): Acts as a precursor for electron-transport materials or host materials in OLED displays and lighting due to its rigid, conjugated structure.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and other functional materials requiring specific electronic properties.
• Chemical Biology & Proteomics: Useful as a molecular probe or tag in biochemical research and assay development.
• Academic & Contract Research: Serves as a valuable reagent for methodological development and novel reaction exploration in synthetic organic chemistry.

Basic Information

Product Name	5-Chloro-6-(Trifluoromethyl)-1H-Indole
CAS No.	1186404-60-3
Molecular Formula	C9H5ClF3N
Molecular Weight	219.59 g/mol
Synonyms	5-Chloro-6-(trifluoromethyl)indole; 1H-Indole, 5-chloro-6-(trifluoromethyl)-; 5-Chloro-6-trifluoromethylindole; 6-Trifluoromethyl-5-chloroindole; 5-Chloro-6-trifluoromethyl-1H-indole
EINECS	Contact for details

Quality Control

Our 5-Chloro-6-(Trifluoromethyl)-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong oxidizers and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.