Description

3-Bromo-5-Chloro-6-(Trifluoromethyl)-1H-Indole is a high-value halogenated indole derivative, a crucial advanced intermediate in modern organic synthesis. Its unique trifluoromethyl and halogen substitution pattern makes it an indispensable building block for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibitors and receptor modulators.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Material Science Precursor: Serves as a starting material for the synthesis of specialized organic electronic materials and functional dyes.
• Chemical Biology Probe Development: Employed in the creation of molecular probes and tags for studying biological systems and pathways.
• Custom Synthesis & Contract Manufacturing: A critical component for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	3-Bromo-5-Chloro-6-(Trifluoromethyl)-1H-Indole
CAS No.	1186404-58-9
Molecular Formula	C9H4BrClF3N
Molecular Weight	298.49 g/mol
Synonyms	3-Bromo-5-chloro-6-(trifluoromethyl)-1H-indole; 1H-Indole, 3-bromo-5-chloro-6-(trifluoromethyl)-; 6-(Trifluoromethyl)-3-bromo-5-chloroindole; 5-Chloro-3-bromo-6-(trifluoromethyl)indole; 3-Bromo-5-chloro-6-trifluoromethylindole
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5-Chloro-6-(Trifluoromethyl)-1H-Indole is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.