Description

Ethyl 5-Amino-1-[4-Bromo-3-(Trifluoromethyl)-Phenyl]-1H-Pyrazole-4-Carboxylate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its molecular architecture, featuring a bromo-trifluoromethylphenyl group and an ester-protected amino pyrazole core, makes it a critical intermediate for developing novel active compounds. This product is primarily needed by research and development teams in the pharmaceutical and agrochemical industries seeking to create new molecules with enhanced biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Serves as a building block for developing new generation herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: Used in the research of advanced organic materials, including liquid crystals and organic semiconductors.
• Chemical Biology: Employed as a probe or scaffold in the study of biological pathways and protein interactions.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	Ethyl 5-Amino-1-[4-Bromo-3-(Trifluoromethyl)-Phenyl]-1H-Pyrazole-4-Carboxylate
CAS No.	1186404-53-4
Molecular Formula	C13H11BrF3N3O2
Molecular Weight	378.15 g/mol
Synonyms	5-Amino-1-[4-bromo-3-(trifluoromethyl)phenyl]-1H-pyrazole-4-carboxylic acid ethyl ester; Ethyl 5-amino-1-(4-bromo-3-trifluoromethylphenyl)pyrazole-4-carboxylate; 1H-Pyrazole-4-carboxylic acid, 5-amino-1-[4-bromo-3-(trifluoromethyl)phenyl]-, ethyl ester; 1186404-53-4; 4-Bromo-3-(trifluoromethyl)phenyl pyrazole ester; ATBPA
EINECS	Contact for details

Quality Control

Every batch of Ethyl 5-Amino-1-[4-Bromo-3-(Trifluoromethyl)-Phenyl]-1H-Pyrazole-4-Carboxylate is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. A comprehensive Certificate of Analysis (COA), detailing purity, identity, and impurity profiles as determined by HPLC, NMR, and MS, is provided with each shipment to guarantee consistent quality and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.