Description

B-(5-Chloro[1,1'-Biphenyl]-3-Yl)Boronic Acid CAS NO 1186403-21-3 is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in enabling the precise construction of complex molecules through reliable cross-coupling reactions. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the biphenyl scaffold for enhanced biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Ligand and Catalyst Development: Employed in the design and synthesis of novel ligands for transition metal catalysis.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Academic & R&D: A valuable reagent for methodological development in synthetic organic chemistry laboratories worldwide.

Basic Information

Product Name	B-(5-Chloro[1,1'-Biphenyl]-3-Yl)Boronic Acid
CAS No.	1186403-21-3
Molecular Formula	C12H10BClO2
Molecular Weight	232.47 g/mol
Synonyms	(5-Chloro-3-biphenylyl)boronic acid; 3-Chloro-5-phenylbenzeneboronic acid; 5-Chloro[1,1'-biphenyl]-3-boronic acid; (3'-Chloro[1,1'-biphenyl]-5-yl)boronic acid; 5-Chloro-3-phenylphenylboronic acid; B-(3'-Chlorobiphenyl-5-yl)boronic acid; 1186403-21-3; 5-Chloro-3-biphenylboronic Acid
EINECS	Contact for details

Quality Control

Our B-(5-Chloro[1,1'-Biphenyl]-3-Yl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.