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(2R)-1-(11Bs)-(Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Yl)-2-Methyl-1,2,3,4-Tetrahydroquinoline, 98% CAS NO 1186392-32-4


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CAS No.:1186392-32-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(2R)-1-(11Bs)-(Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Yl)-2-Methyl-1,2,3,4-Tetrahydroquinoline, 98% is a high-purity, chiral organophosphorus compound of significant interest in advanced synthetic chemistry. Its value lies in its role as a sophisticated ligand precursor or catalyst for asymmetric transformations, enabling the production of enantiomerically enriched molecules. This product is essential for R&D and process chemistry teams in the pharmaceutical and fine chemical industries, where precise stereochemical control is paramount.

Application

  • Asymmetric Catalysis: Serving as a key ligand or catalyst precursor in transition-metal catalyzed reactions such as hydrogenation, hydroformylation, or cross-coupling to create chiral intermediates.
  • Pharmaceutical Intermediate Synthesis: Enabling the stereoselective construction of complex active pharmaceutical ingredients (APIs) and drug candidates.
  • Agrochemical Research: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
  • Material Science: Potential application in the synthesis of chiral polymers or as a component in advanced catalytic systems for specialty materials.
  • Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and catalysis research.

Basic Information

Product Name (2R)-1-(11Bs)-(Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Yl)-2-Methyl-1,2,3,4-Tetrahydroquinoline, 98%
CAS No. 1186392-32-4
Molecular Formula C31H24NO2P
Molecular Weight 473.50 g/mol
Synonyms (2R)-2-Methyl-1-(4-((11bS)-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl))-1,2,3,4-tetrahydroquinoline; (R)-2-Methyl-1-((S)-4-(dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl))-1,2,3,4-tetrahydroquinoline; (S)-4-((R)-2-Methyl-1,2,3,4-tetrahydroquinolin-1-yl)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine; Quinoline-based BINOL phosphite ligand; Chiral phosphite ligand; CAS 1186392-32-4
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Quality Control

This product is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Every lot is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, enantiomeric excess, and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Enantiomeric Excess (Chiral HPLC) ≥ 99.0% ee
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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