Description

2-Ethoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazine is a high-value, synthetically versatile organoboron building block. This compound matters as a critical intermediate in modern cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds essential for advanced material and life science research. Pharmaceutical, agrochemical, and material science R&D teams need it for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those containing functionalized pyrazine cores.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific heterocyclic architectures.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic semiconductors.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and labeled compounds for studying biological processes and target engagement.
• Academic & Contract Research: Essential for methodology development and synthetic chemistry research in academic and industrial R&D laboratories.

Basic Information

Product Name	2-Ethoxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyrazine
CAS No.	1186041-95-1
Molecular Formula	C12H19BN2O3
Molecular Weight	250.10 g/mol
Synonyms	2-Ethoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazine; 5-Ethoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazine; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-ethoxypyrazine; Pyrazine, 2-ethoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 1186041-95-1; 2-Ethoxy-5-pyrazineboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Ethoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C (refrigerated).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.