Description

Pentoxifylline-D6 is a deuterium-labeled analog of the vasodilator and hemorheological agent pentoxifylline, specifically designed for use as an internal standard in analytical chemistry. This high-purity, isotopically labeled compound is critical for ensuring accuracy and reliability in quantitative mass spectrometry and pharmacokinetic studies. It is an essential tool for pharmaceutical research and development, clinical laboratories, and regulatory agencies involved in drug metabolism and bioanalytical method validation.

Application

• Internal Standard for LC-MS/MS and GC-MS quantification of pentoxifylline in biological matrices (plasma, serum, urine).
• Metabolite tracking and pharmacokinetic studies in drug development and clinical research.
• Bioanalytical method development and validation for regulatory submissions (FDA, EMA).
• Isotope dilution mass spectrometry (IDMS) for high-precision quantitative analysis.
• Stability studies and degradation pathway elucidation of pentoxifylline formulations.
• Use in forensic and anti-doping analysis for precise measurement.

Basic Information

Product Name	Pentoxifylline-D6
CAS No.	1185878-98-1
Molecular Formula	C13H12D6N4O3
Molecular Weight	284.33 g/mol
Synonyms	1-(5-Oxohexyl)-3,7-dimethyl-2,3,6,7,8,8a-hexahydro-1H-purine-2,6-dione-d6; 3,7-Dimethyl-1-(5-oxohexyl)-3,7-dihydro-1H-purine-2,6-dione-d6; Oxpentifylline-d6; Trental-d6; BL 191-d6; [D6]-Pentoxifylline; Deuterated Pentoxifylline
EINECS	Contact for details

Quality Control

Our Pentoxifylline-D6 is manufactured under strict quality control protocols to ensure the highest isotopic purity and chemical integrity required for analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically ≥98% D), chemical purity (by HPLC), and confirming identity via spectroscopic methods. We adhere to relevant industry standards for reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This material is hygroscopic (moisture-sensitive) and must be kept under inert conditions or desiccated after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (D)	≥98 atom % D
Chemical Purity	≥95%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.