Description

5-Methyl-2-(Pyrrolidin-2-Yl)-1H-Benzo[D]Imidazole Dihydrochloride is a high-purity, pharmaceutically relevant organic salt, primarily valued as a key intermediate in the synthesis of complex active pharmaceutical ingredients (APIs). Its significance lies in its role as a versatile building block for constructing molecules with potential biological activity, particularly within the benzimidazole class. This compound is essential for research and development chemists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly those targeting various therapeutic areas.
• Biochemical Research: Used as a reference standard or precursor in medicinal chemistry programs and pharmacological studies.
• Organic Synthesis: Serves as a versatile scaffold for constructing complex heterocyclic compounds in academic and industrial R&D laboratories.
• API Development: Employed in the process development and scale-up of potential Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Can be utilized to develop molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	5-Methyl-2-(Pyrrolidin-2-Yl)-1H-Benzo[D]Imidazole Dihydrochloride
CAS No.	1185692-43-6
Molecular Formula	C₁₂H₁₆N₃·2HCl
Molecular Weight	287.19 g/mol (free base: 202.27 g/mol)
Synonyms	5-Methyl-2-(2-pyrrolidinyl)-1H-benzimidazole dihydrochloride; 2-(2-Pyrrolidinyl)-5-methyl-1H-benzimidazole dihydrochloride; 5-Methyl-2-(pyrrolidin-2-yl)-1H-benzo[d]imidazole dihydrochloride; 1H-Benzimidazole, 5-methyl-2-(2-pyrrolidinyl)-, dihydrochloride; Benzimidazole derivative 1185692-43-6
EINECS	Contact for details

Quality Control

Our 5-Methyl-2-(Pyrrolidin-2-Yl)-1H-Benzo[D]Imidazole Dihydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis. A Certificate of Analysis (COA) is supplied with each batch to document compliance with our stringent specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.