Description

3-Acetyl-6-(Methyl-D3)-Pyridine is a deuterium-labeled derivative of 3-acetylpyridine, a compound of significant interest in advanced chemical research and development. This isotopically labeled compound is specifically designed for use as a stable internal standard in mass spectrometry, enabling precise quantification and reliable metabolic pathway analysis. It is an essential tool for researchers and analytical chemists in the pharmaceutical, agrochemical, and life science industries who require high-fidelity standards for method development and regulatory compliance.

Application

• Pharmaceutical Research: Serves as a critical stable isotope-labeled internal standard (SIL-IS) in LC-MS/MS and GC-MS methods for the bioanalysis and pharmacokinetic (PK) studies of drug candidates and metabolites.
• Metabolomics & Proteomics: Used in quantitative mass spectrometry to trace metabolic pathways, study enzyme kinetics, and ensure accurate quantification of biomarkers in complex biological matrices.
• Agrochemical Development: Employed in the analysis of pesticide residues, environmental fate studies, and the development of analytical methods for regulatory submission.
• Chemical Synthesis: Acts as a deuterated building block for the synthesis of more complex labeled compounds, facilitating research in reaction mechanisms and material science.
• Forensic & Clinical Toxicology: Provides a reliable reference standard for the accurate identification and quantification of substances in forensic analysis and clinical diagnostic assays.
• Academic Research: Supports fundamental research in chemistry and biochemistry where isotopic labeling is required to elucidate reaction pathways or molecular interactions.

Basic Information

Product Name	3-Acetyl-6-(Methyl-D3)-Pyridine
CAS No.	1185314-07-1
Molecular Formula	C8H6D3NO
Molecular Weight	138.18 g/mol
Synonyms	1-[6-(Trideuteriomethyl)pyridin-3-yl]ethanone; 3-Acetyl-6-(trideuteriomethyl)pyridine; 6-(Methyl-d3)-3-acetylpyridine; Deuterated 3-Acetyl-6-methylpyridine; 3-Acetyl-6-methyl-d3-pyridine; 3-Acetyl-6-(CD3)-pyridine; 3-Acetyl-6-methylpyridine-d3
EINECS	Contact for details

Quality Control

Every batch of 3-Acetyl-6-(Methyl-D3)-Pyridine is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We guarantee high chemical purity and isotopic enrichment to meet the exacting requirements of analytical reference standards. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity (by HPLC), isotopic purity (by NMR/MS), and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere or in a moisture-controlled environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.